清く美しく生きるための探究。
Ninety days, and seven markers.
HIKYAKU's Ninety-Day Trial is not a before-and-after photo program — it's a blood-test verdict. Why ninety days, why seven markers, why four passes mean success. The biochemistry behind the design.
514 kilometers, from Nihonbashi to Kyoto.
The fifty-four stations of the Tōkaidō — 514 kilometers. The Edo-era couriers' path, translated into the metabolic journey of modern life. Why the metaphor of distance shapes habit, the dopamine reward system, and the goal-gradient effect.
Folate has two faces.
In the drugstore, two folate supplements sit side by side — 'Folic Acid' and '5-MTHF.' The MTHFR gene polymorphism carried by roughly half of Japanese people, the folate cycle, methylation, and neurotransmitters. Not 'does it work,' but 'does it arrive.'
Four paths, four bodies.
Light Keto, Keto Body, Town Courier, Express Courier — HIKYAKU's four modes are not just different fasting hours. From 12 to 23 hours, each step represents a distinct biochemical state. The hormonal staircase, read carefully.
The scale of mTOR — between growth and repair.
'Eat enough protein' and 'fasting extends life' sound contradictory. Standing between them is mTOR — the cellular switch that toggles between activation and suppression. How to read the annual balance, and what longevity research reveals.
Forty, in the valley of doubt.
Confucius said: 'At forty, I had no doubts.' Yet modern well-being data shows that the forties are the most uncertain years of life. The real meaning of 'no doubt,' the U-curve of happiness, and what's happening at the cellular level.
Know before you add — the margins of 'normal' and the science of where you stand
The margins of a 'normal' blood test still hold a question. The gap between clinical reference ranges and precision-nutrition ideals, the metabolism of carbohydrates, the 2026 shift in US dietary guidance — and the distance of 66 days.
On balance — what an acupuncturist in Barcelona saw through me
In a life tilted toward digital, what is the body seeking? An acupuncturist in Barcelona told me my cranial pressure was dangerously high. From that encounter, reflections on chronic stress and precision nutrition.
Is HbA1c 5.4% 'normal'? — Why precision nutrition targets ≤ 5.3%
Clinical medicine calls HbA1c under 5.7% 'normal.' Precision nutrition sets the ideal at 5.0–5.3%. Where does that difference come from?
How sound reaches the body — speakers, the vagus nerve, and the parasympathetic system
Sound from a good speaker doesn't just vibrate the eardrum. Via the vagus nerve, it activates the parasympathetic system, shifts HRV, and modulates cortisol. Listening is choosing input for your nervous system.
When does illness begin?
My grandmother died of colon cancer. When she was diagnosed at Stage 4, did the illness start there — or had it begun long before? On prevention, and why I built this app.
Your afternoon coffee and the adenosine receptors
What decides when you drink coffee? Not the clock — but the interplay of adenosine accumulation and circadian cortisol rhythm. Reverse-engineering the optimal cup.
For those it reaches — on starting this blog
Starting a blog in the age of social media. A choice to write in serotonin time, not dopamine time.